Over time, that aggressive autophagy can kill neurons — a major cell type in the brain, Guha told Mic via email. The findings are a missing puzzle piece. In , the Johns Hopkins research team found that brain cells communicate using a gas called nitric oxide, the press release said.
In , they found that cocaine-induced cell death had something to do with an interaction between nitric oxide and an enzyme called GAPDH. But they still didn't know exactly how the cells were dying.
William D. Sadly, cell death isn't the only harmful health effect of cocaine use, as Stanley pointed out. Other long-term effects could include weight loss, dementia and psychiatric complications including paranoia, psychosis and auditory hallucinations, he said.
Here's what comes next for the John Hopkins research team. Now that the researchers know the truth about cocaine — that it makes brain cells voraciously chow down on themselves, pretty much — they can better search for ways to combat cocaine's toxic effects. This time around, they tested the compound's ability to halt cocaine-induced autophagy, and found that it "protected mouse nerve cells in the brain from death by cocaine," the release said. Harraz, a research associate at Johns Hopkins and lead co-author of the paper, said.
Though Guha and his team still need to conduct further research, the findings involving CGPB are "promising," he told Mic. For now, it's good to know cocaine use in the U.
In , the number of users aged 12 or older was 1. That's lower than the period between and , when the number of users reportedly ranged from 2.
The material girl was really feeling herself in her latest photoshoot. Six other highschoolers who watched the show have been sentenced to hard labor. Their teachers have been fired and may be sent to work in remote mines. A pregnant woman in Florida died after a heated and violent interaction with a motorcyclist on the road Saturday. Sara Nicole Morales allegedly intentionally hit motorcyclist Andrew Derr in her car, the Orange City Police Department said, according to a statement on posted to Facebook.
Derr was not injured, and he and other witnesses followed Morales after she started to drive away, according to authorities. The police said Morales drove to her Seth Curry had no idea where his brother Steph was on this play. Where does that leave Cup Series lineups before ? In the wake of Steven Matz signing with the St. Video footage shows a menacing-looking sea creature with a gaping mouth full of fang-like teeth that mysteriously washed ashore alive. The "Late Show" host has a mock plea from one of the former president's sons.
Elizabeth Hurley dons Fendi sunglasses and a striped bikini in a new Instagram pic. The Red Notice star surprised the Navy vet with a new truck after learning of his good deeds.
The Duchess of Cambridge joined a group of young students as they learned about neuroscience and the importance of early childhood development. Her outfit consisted of a beautiful cranberry-colored crimson coat with a matching roll neck jumper by Hobbs. She paired the look with black trousers and a pair of her signature pointed-toe black suede pumps. US retailers are struggling to find and retain workers who have been put off by low pay, a lack of benefits, and pandemic health concerns.
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